Question

Penicillin degradation is prevented at which pH?

• A. \( \text{4} \)
• B. \( \text{5} \)
• C. \( \text{6} \)
• D. \( \text{8} \)

Hint:

Penicillin degradation occurs faster in acidic and alkaline environments due to hydrolysis.

Answer 1

The Correct Option is C

Penicillin stability is highest at pH 6, where hydrolysis is minimal. At extreme pH values, such as acidic or basic conditions, penicillin undergoes decomposition due to β-lactam ring cleavage. Maintaining optimal pH ensures drug efficacy and shelf-life preservation.