Question

Oxidative decarboxylation of pyruvic acid results in the formation of I. $\quad$Acetyl CoA II. $\quad$C0$^2$ III. $\quad$ATP IV. $\quad$NADH + H$_+$

• A. I only
• B. I and II only
• C. I, II and III only
• D. I,II and IV only

Answer 1

The Correct Option is D

Pyruvate formed during glycolysis enters mitochondrial matrix and undergoes oxidative decarboxylation by a complex set of reactions catalysed by pyruvic dehydrogenase and NADH, acetyl CoA and $CO_2$ is produced. Pyruvic $+ CoA + NAD^+ {->[Mg^{2+}][\text{Pyruvate dehydrogenase}]}$ Acetyl $CoA + CO_2 + NADH+ H^+$ Acetyl CoA enters the TCA cycle.