Question

One of the following is NOT an antigen presenting cell.

• A. B cells
• B. Dendritic cells
• C. Macrophages
• D. T cells

Hint:

Antigen-presenting cells (APCs) include B cells, dendritic cells, and macrophages, while T cells play the role of recognizing presented antigens.

Answer 1

The Correct Option is D

Antigen-presenting cells (APCs) are responsible for capturing, processing, and presenting antigens to T-cells.
(1) B cells: B cells can act as antigen-presenting cells (APCs) by capturing antigens and presenting them on MHC class II molecules to activate T-cells.
(2) Dendritic cells: Dendritic cells are the most efficient antigen-presenting cells, capturing antigens and presenting them to T-cells.
(3) Macrophages: Macrophages also function as antigen-presenting cells, phagocytizing pathogens and presenting antigens to T-cells.
(4) T cells: T cells are not antigen-presenting cells. They respond to antigens presented by other cells like B cells, dendritic cells, or macrophages.
Conclusion: The correct answer is Option 4: T cells because they do not function as antigen-presenting cells.