Question:
Which of the following best explains the absence of immune response to self-antigens under normal physiological conditions?
Which of the following best explains the absence of immune response to self-antigens under normal physiological conditions?
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Clonal deletion is essential in maintaining self-tolerance and preventing autoimmune diseases.
Updated On: Jun 18, 2025
- Clonal expansion
- Clonal deletion
- Somatic recombination
- Affinity maturation
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The Correct Option is B
Solution and Explanation
The process of clonal deletion involves the removal of self-reactive T and B cells during the development of immune cells, preventing the immune system from attacking the body's own tissues. This process ensures that self-antigens do not provoke an immune response under normal physiological conditions.
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