Question:

Observe the given diagram and answer the following questions. 
(Note: This question refers to the mice experiment with S-strain and R-strain bacteria) 

a) Who performed this experiment? 
b) What was the conclusion after this experiment? 
c) Write the results of the experiment A - D 
 

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Griffith's experiment did not identify the biochemical nature of the transforming principle (DNA). That was later discovered by Avery, MacLeod, and McCarty.
Updated On: Jan 6, 2026
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Solution and Explanation

Step 1: (a) This experiment was performed by Frederick Griffith in 1928 using Streptococcus pneumoniae bacteria and mice.
Step 2: (b) The conclusion was that the R-strain bacteria had somehow been transformed by the heat-killed S-strain bacteria. He stated that some "transforming principle" transferred from the heat-killed S-strain enabled the R-strain to synthesize a smooth polysaccharide coat and become virulent.
Step 3: (c) In Experiment A, when mice were injected with the virulent S-strain (smooth, polysaccharide coat), they developed pneumonia and died.
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