Question

Match List-I with List-II:

List-I (Genes/Products)	List-II (Used in/for)
(A) C-Peptide	(I) Corn borer
(B) α-1-antitrypsin	(II) Rosie
(C) cryIAc	(III) Insulin
(D) α-lactalbumin	(IV) Emphysema

• A. (A)-(IV), (B)-(III), (C)-(I), (D)-(II)
• B. (A)-(III), (B)-(IV), (C)-(I), (D)-(II)
• C. (A)-(III), (B)-(IV), (C)-(II), (D)-(I)
• D. (A)-(II), (B)-(I), (C)-(IV), (D)-(III)

Answer 1

The Correct Option is B

Let's match the genes/products with their corresponding uses:

(A) C-Peptide: C-Peptide is a part of insulin that is released from the pancreas. It is cleaved from the proinsulin molecule and is used as a marker in monitoring insulin production. Thus, (A)-(III) is correct, as C-Peptide is related to insulin.

(B) α-1-antitrypsin: This protein is used in the treatment of emphysema, a lung condition often caused by a deficiency of this protein. It is used as a therapeutic product to prevent damage to lung tissue. Thus, (B)-(IV) is correct, as α-1-antitrypsin is used for treating emphysema.

(C) cryIAc: CryIAc is a Bt toxin protein produced by the bacterium Bacillus thuringiensis, which is used as an insecticide, particularly for targeting pests like the corn borer. Thus, (C)-(I) is correct, as cryIAc is used for the corn borer.

(D) α-lactalbumin: α-lactalbumin is a protein found in milk, and it has been used in genetic modifications to produce Rosie, the genetically modified cow that produces human-like milk for pharmaceuticals. Thus, (D)-(II) is correct, as α-lactalbumin is associated with Rosie.

Thus, the correct matching is:

(A)-(III): C-Peptide → Insulin

(B)-(IV): α-1-antitrypsin → Emphysema

(C)-(I): cryIAc → Corn borer

(D)-(II): α-lactalbumin → Rosie

The correct answer is (2) (A)-(III), (B)-(IV), (C)-(I), (D)-(II).