Question

Match List-I with List-II:

List-I (Genes/Products)	List-II (Used in/for)
(A) C-Peptide	(I) Corn borer
(B) α-1-antitrypsin	(II) Rosie
(C) cryIAc	(III) Insulin
(D) α-lactalbumin	(IV) Emphysema

• A. (A)-(IV), (B)-(III), (C)-(I), (D)-(II)
• B. (A)-(III), (B)-(IV), (C)-(I), (D)-(II)
• C. (A)-(III), (B)-(IV), (C)-(II), (D)-(I)
• D. (A)-(II), (B)-(I), (C)-(IV), (D)-(III)

Answer 1

The Correct Option is B

To correctly match List-I with List-II, we need to understand the association between the genes/products and their applications or uses:

(A) C-Peptide: C-Peptide is a part of the proinsulin molecule, and its primary use is related to insulin. Therefore, it matches with (III) Insulin.

(B) α-1-antitrypsin: This is a protein that protects tissues from enzyme damage, particularly used in the treatment of emphysema related to α-1-antitrypsin deficiency. Thus, it matches with (IV) Emphysema.

(C) cryIAc: This gene is derived from Bacillus thuringiensis and is used in genetically modified crops to confer resistance to certain pests, like the corn borer. So, it matches with (I) Corn borer.

(D) α-lactalbumin: This protein is associated with milk production in mammals and is linked to the transgenic cow named Rosie, which produced milk with higher nutrition. Therefore, it matches with (II) Rosie.

Thus, the correct set of matches is (A)-(III), (B)-(IV), (C)-(I), (D)-(II).

Answer 2

Let's match the genes/products with their corresponding uses:

(A) C-Peptide: C-Peptide is a part of insulin that is released from the pancreas. It is cleaved from the proinsulin molecule and is used as a marker in monitoring insulin production. Thus, (A)-(III) is correct, as C-Peptide is related to insulin.

(B) α-1-antitrypsin: This protein is used in the treatment of emphysema, a lung condition often caused by a deficiency of this protein. It is used as a therapeutic product to prevent damage to lung tissue. Thus, (B)-(IV) is correct, as α-1-antitrypsin is used for treating emphysema.

(C) cryIAc: CryIAc is a Bt toxin protein produced by the bacterium Bacillus thuringiensis, which is used as an insecticide, particularly for targeting pests like the corn borer. Thus, (C)-(I) is correct, as cryIAc is used for the corn borer.

(D) α-lactalbumin: α-lactalbumin is a protein found in milk, and it has been used in genetic modifications to produce Rosie, the genetically modified cow that produces human-like milk for pharmaceuticals. Thus, (D)-(II) is correct, as α-lactalbumin is associated with Rosie.

Thus, the correct matching is:

(A)-(III): C-Peptide → Insulin

(B)-(IV): α-1-antitrypsin → Emphysema

(C)-(I): cryIAc → Corn borer

(D)-(II): α-lactalbumin → Rosie

The correct answer is (2) (A)-(III), (B)-(IV), (C)-(I), (D)-(II).