Question:

Major gluconeogenesis occurs in:

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Gluconeogenesis primarily occurs in the liver and kidney, not in muscle or heart tissue.
Updated On: Jun 18, 2025
  • Liver and kidney
  • Liver and heart
  • Liver and skeletal muscle
  • Liver and adrenal gland
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The Correct Option is A

Solution and Explanation

Gluconeogenesis primarily occurs in the liver and kidneys, where precursors like lactate and glycerol are converted into glucose. While muscle tissue can generate glucose-6-phosphate, it does not have the enzyme glucose-6-phosphatase needed to produce free glucose. The heart and adrenal glands are not major sites of gluconeogenesis.
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