Question

In which medium does the Favorskii rearrangement occur?

• A. \( \text{Neutral} \)
• B. \( \text{Acidic} \)
• C. \( \text{Basic} \)
• D. \( \text{Amphiprotic} \)

Hint:

The Favorskii rearrangement is widely used in organic synthesis for ring contraction and carboxylate formation.

Answer 1

The Correct Option is C

The Favorskii rearrangement occurs in a basic medium, typically under alkaline conditions. It involves the conversion of α-haloketones to carboxylic acids or esters via enolate intermediates. Base facilitates nucleophilic attack, forming cyclic or acyclic rearrangement products.