Question

Immune marker for lactotroph adenoma is:

• A. Growth hormone
• B. $\beta$ - TSH
• C. Adrenocorticotropic hormone
• D. Prolactin

Hint:

Pituitary adenomas are identified by their hormone marker: Prolactin for lactotroph, GH for somatotroph, ACTH for corticotroph, TSH for thyrotroph.

Answer 1

The Correct Option is D

Step 1: Recall pituitary adenomas.
Pituitary adenomas are classified according to the predominant hormone secreted. They can be functional (hormone-secreting) or non-functional.
Step 2: Understand lactotroph adenomas.
Lactotroph adenomas are prolactin-secreting pituitary tumors. They are the most common type of pituitary adenoma and result in hyperprolactinemia.
Clinical features include galactorrhea, amenorrhea, infertility, and hypogonadism.
Step 3: Analyze the options.
- (A) Growth hormone: Marker for somatotroph adenomas, not lactotrophs.
- (B) $\beta$-TSH: Marker for thyrotroph adenomas.
- (C) ACTH: Marker for corticotroph adenomas.
- (D) Prolactin: Correct marker for lactotroph adenoma.
Step 4: Conclusion.
The immune marker for lactotroph adenoma is Prolactin.