Step 1: Initial clot formation.
The process begins with the formation of a blood clot in the blood vessels (C).
Step 2: Movement of clot.
The clot then travels to the brain via circulation (A).
Step 3: Effect on brain cells.
Due to ischemia, brain cells begin to undergo lysis as they are deprived of oxygen and nutrients (D).
Step 4: Systemic response.
In response, blood pressure increases (B), putting extra stress on cerebral vessels.
Step 5: Final outcome.
Eventually, the blood vessels rupture (E), leading to haemorrhagic transformation.
Step 6: Conclusion.
The correct sequence is C $\rightarrow$ A $\rightarrow$ D $\rightarrow$ B $\rightarrow$ E.