Question

Identify the incorrect statements regarding the immune system.
I. Immunity developed by individual due to vaccination is artificial passive acquired immunity.
II. Interleukins are involved in differentiation of immune cells.
III. Large granular lymphocytes destroy infected cell in an antibody dependent manner.
IV. Mature lymphocytes transform into functional lymphocytes in Peyer's patches.

• A. I, III
• B. II, IV
• C. I, II
• D. III, IV

Hint:

Understanding the different types of immunity and cellular functions within the immune system is fundamental for comprehending how the body fights disease.

Answer 1

The Correct Option is A

Step 1: Statement I is incorrect. Immunity developed due to vaccination is called artificial active acquired immunity, not passive immunity. Passive immunity involves the transfer of pre-formed antibodies (e.g., from mother to child), whereas active immunity is induced by vaccination where the individual’s immune system produces antibodies. 
Step 2: Statement II is correct. Interleukins are indeed involved in the differentiation and activation of immune cells. They are signaling molecules that help coordinate immune responses. 
Step 3: Statement III is incorrect. Large granular lymphocytes, such as Natural Killer (NK) cells, destroy infected cells in an antibody-independent manner. They do not require antibodies to recognize and kill infected cells; they recognize abnormal cells through various receptors. 
Step 4: Statement IV is correct. Mature lymphocytes do transform into functional lymphocytes in structures such as Peyer's patches. These lymphoid tissues are located in the intestines and play a critical role in the immune system, especially in the mucosal immunity. 
Conclusion: The incorrect statements are I and III, making (1) I, III the correct answer.