Question:

Identify the correctly matched pair of substances with their renal clearance from the graph below.
renal clearance

Updated On: Jun 18, 2025
  • A-Glucose, B-PAH, C- Bicarbonate and D - Inulin
  • A-Glucose, B- Bicarbonate, C-Inulin and D - PAH
  • A-PAH, B-Inulin, C - Glucose and D - Bicarbonate
  • A - Inulin, B - Glucose, C - Bicarbonate and D - PAH
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The Correct Option is B

Solution and Explanation

To determine the correctly matched pair of substances with their renal clearance, we need to understand the concept of renal clearance and the substances commonly involved in renal physiology. Renal clearance measures the volume of plasma cleared of a substance per unit time. Here's how we can match each substance:
  • Glucose: Glucose is typically reabsorbed completely in the renal tubules during normal physiological conditions, resulting in a renal clearance of zero.
  • Bicarbonate: Bicarbonate is also reabsorbed almost completely under normal conditions, resulting in low renal clearance.
  • Inulin: Inulin is neither secreted nor reabsorbed, so it has a renal clearance equal to the glomerular filtration rate (GFR).
  • PAH (Para-aminohippuric acid): PAH is used to measure renal plasma flow because it is both filtered and secreted by the renal tubules, leading to a high renal clearance value.
Based on the renal clearance characteristics, the correct matching from the graph is: A-Glucose, B-Bicarbonate, C-Inulin and D-PAH.
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