Question:

Which of the following vaccines is kept at the lowest level? 

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The OPV requires the lowest temperature in the vaccine cold chain, so ensure it is stored at -20°C to -30°C for optimal efficacy.
Updated On: Jul 9, 2025
  • OPV
  • DPT
  • Hep B
  • Rota
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The Correct Option is A

Solution and Explanation

Explanation: In the context of vaccine storage, it is crucial to maintain vaccines at specific temperature ranges to preserve their efficacy and potency. Among the vaccines listed, Oral Polio Vaccine (OPV) is known to be the most temperature-sensitive.

OPV needs to be stored at the coldest temperatures, typically between -15°C and -25°C. This is because OPV is a live attenuated vaccine, meaning it contains weakened forms of the virus that can become ineffective if not stored properly. The ultra-cold storage requirements help in preserving its live virus components effectively.

VaccineStorage Temperature
OPV-15°C to -25°C
DPT2°C to 8°C
Hep B2°C to 8°C
Rota2°C to 8°C

As shown in the table above, OPV is stored at the lowest temperature compared to DPT, Hep B, and Rota vaccines, which are stored within a range of 2°C to 8°C.

Therefore, the correct answer is OPV.

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