Question

Hand-foot syndrome (palmar-plantar erythrodysesthesia) is NOT caused by:

• A. \( \text{5-fluorouracil} \)
• B. \( \text{Capecitabine} \)
• C. \( \text{Mitomycin} \)
• D. \( \text{Doxorubicin} \)

Hint:

Reducing prolonged exposure to chemotherapy agents and applying supportive skin care can alleviate hand-foot syndrome.

Answer 1

The Correct Option is C

Hand-foot syndrome is a dermatological reaction associated with certain chemotherapy drugs like 5-fluorouracil, capecitabine, and doxorubicin. Mitomycin, a DNA cross-linking agent, is not a primary cause of this syndrome but has other toxic effects. Proper dosage adjustments and supportive care can mitigate hand-foot syndrome in patients undergoing chemotherapy.