Question

Given below are two statements - one is labelled as Assertion (A) and the other is labelled as Reason (R) 
Assertion (A): In the eukaryotic genes, TATA box aids in transcription. 
Reason (R): The TATA box facilitates formation of pre-initiation complex for transcription initiation. 
In light of the above statements, choose the most appropriate answer from the options given below.

• A. Both A and R are correct and R is the correct explanation of A
• B. Both A and R are correct, but R is NOT the correct explanation of A
• C. A is correct but R is not correct
• D. A is not correct but R is correct

Hint:

In transcription, the TATA box serves as a binding site for transcription factors and RNA polymerase, facilitating the formation of the pre-initiation complex and the initiation of transcription.

Answer 1

The Correct Option is A

Step 1: Understand the role of TATA box.
The TATA box is a DNA sequence found in the promoter region of eukaryotic genes. It plays a crucial role in transcription initiation by serving as a binding site for transcription factors and RNA polymerase.

Step 2: Explanation of the assertion (A).
Assertion (A) is correct because the TATA box is involved in the transcription process. It helps in positioning the transcription machinery and aids the initiation of transcription in eukaryotic genes.

Step 3: Explanation of the reason (R).
Reason (R) is also correct because the TATA box is involved in the formation of the pre-initiation complex, a necessary step for transcription to begin. The pre-initiation complex includes the binding of RNA polymerase and other transcription factors, which is critical for the initiation of transcription.

Step 4: Relationship between A and R.
Since both the assertion and reason are correct and the reason directly explains why the TATA box aids in transcription (formation of the pre-initiation complex), R is the correct explanation of A.