Question

Genes which control $\alpha$-Thalassemia and $\beta$-Thalassemia are present on which number of chromosomes?

• A. On 16 \& on 21
• B. On 21 \& on 11
• C. On 16 \& on 11
• D. On 11 \& on 16

Hint:

Remember: $\alpha$ = Chromosome 16, $\beta$ = Chromosome 11 in thalassemia genetics.

Answer 1

The Correct Option is C

- $\alpha$-Thalassemia is caused by mutations/deletions in genes located on chromosome 16.
- $\beta$-Thalassemia is caused by mutations in the $\beta$-globin gene located on chromosome 11.
Therefore, both 16 and 11 are involved in respective forms of thalassemia.