Question

Fluoroquinolones with maximum bioavailability is?

• A. Moxifloxacin
• B. Gatifloxacin
• C. Levofloxacin
• D. Ciprofloxacin

Answer 1

The Correct Option is C

Fluoroquinolones are a class of antibiotics used to treat a variety of bacterial infections. One important pharmacokinetic property of these drugs is their bioavailability, which indicates the extent and rate at which the active drug enters systemic circulation, thereby becoming available at the site of action.

Among the options given:

• Moxifloxacin
• Gatifloxacin
• Levofloxacin
• Ciprofloxacin

Levofloxacin is known for having the highest bioavailability when taken orally. It is nearly 100% bioavailable, meaning that when absorbed, it reaches almost the same concentration in the bloodstream as when administered intravenously. This characteristic makes levofloxacin particularly effective for oral administration, providing flexibility in treatment regimens.

In conclusion, the fluoroquinolone with maximum bioavailability is Levofloxacin.