Type II hypersensitivity:
- Is antibody independent
- Is complement independent
- Is mediated by CD8+ cells
Involves antibody-mediated destruction of cells
The Correct Option is D
Solution and Explanation
Step 1: Understanding Type II hypersensitivity. - Type II hypersensitivity is an antibody-mediated reaction where IgG or IgM antibodies target specific cells, leading to cell destruction. - This destruction occurs via complement activation, opsonization, or antibody-dependent cellular cytotoxicity (ADCC).
Step 2: Explanation of incorrect options. - Antibody independent (A): Incorrect because antibodies (IgG, IgM) play a central role in this reaction.
- Complement independent (B): Incorrect because complement activation contributes to cell lysis.
- Mediated by CD8+ cells (C): Incorrect because CD8+ T cells are involved in Type IV hypersensitivity, not Type II.
Step 3: Selecting the correct option. Since Type II hypersensitivity is characterized by antibody-mediated destruction of cells, the correct answer is (D) Involves antibody-mediated destruction of cells.
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