Question:

Damage to thymus in a child may lead to

Updated On: Apr 18, 2024
  • Reduction in haemoglobin content of blood
  • Reduction in stem cell production
  • Loss of antibody mediated immunity
  • Loss of cell mediated immunity
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The thymus is the major gland of our immune system. The thymus is responsible for many immune system functions including the production of T-lymphocytes, a type of white blood cell responsible for cell mediated immunity. Cell mediated immunity is a type of immunity in which specialized cells carry' out defensive activities. They protect the body against pathogens including the protists and fungi which have entered the host's cells. T-cells and B-cells are the type of lymphocytes that develop from bone marrow cells. Those lymphocytes that migrate to the thymus and differentiate are called T-cells and those cells that continue to be in the bone marrow for differentiation are known as B-cells. T-cells are responsible for cell mediated immunity, however, B- cells produce antibodies and take part in antibody mediated immunity.
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The thymus gland is positioned behind the sternum in the chest. T-cells are produced in the bone marrow. These cells go to the thymus. The thymus gland is in charge of T-cell differentiation and maturation. To combat infections, these mature T-cells are discharged into the circulation. T-cells collaborate with B-cells to eliminate bacteria, viruses, and other foreign antigens. Any injury to the thymus during childhood may result in a shortage or a lower number of mature T-cells. This makes the youngster more susceptible to illnesses. As a result, there will be a shortage or loss of T-cell-mediated immunity.
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