The thymus gland is positioned behind the sternum in the chest. T-cells are produced in the bone marrow. These cells go to the thymus. The thymus gland is in charge of T-cell differentiation and maturation. To combat infections, these mature T-cells are discharged into the circulation. T-cells collaborate with B-cells to eliminate bacteria, viruses, and other foreign antigens. Any injury to the thymus during childhood may result in a shortage or a lower number of mature T-cells. This makes the youngster more susceptible to illnesses. As a result, there will be a shortage or loss of T-cell-mediated immunity.