Question

Chromosome involved in myotonic dystrophy is

• A. Chromosome 19
• B. Chromosome 20
• C. Chromosome 21
• D. Chromosome 22

Answer 1

The Correct Option is A

Myotonic dystrophy is a genetic disorder characterized by progressive muscle wasting and weakness. The condition is caused by mutations in specific genes. The gene responsible for myotonic dystrophy type 1, which is the most common form, is the DMPK gene.

This gene is located on Chromosome 19, specifically at the 19q13.32 region. Mutations in this gene, often involving an abnormal expansion of a CTG trinucleotide repeat, lead to the symptoms associated with myotonic dystrophy.

Thus, when considering the options provided:

Options	Description
Chromosome 19	Correct - Contains the DMPK gene linked to Myotonic Dystrophy.
Chromosome 20	Incorrect
Chromosome 21	Incorrect
Chromosome 22	Incorrect

In summary, the chromosome involved in myotonic dystrophy is Chromosome 19, due to the location of the DMPK gene.