Question

Assertion (A): Aromatic primary amines cannot be prepared by Gabriel Phthalimide synthesis. Reason (R): Aryl halides do not undergo nucleophilic substitution reaction with the anion formed by phthalimide.

• A. Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of the Assertion (A).
• B. Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation of the Assertion (A).
• C. Assertion (A) is true, but Reason (R) is false.
• D. Assertion (A) is false, but Reason (R) is true.

Hint:

The Gabriel synthesis is an effective method for preparing primary amines from alkyl halides, but it does not work well with aryl halides due to their poor reactivity in nucleophilic substitution reactions.

Answer 1

The Correct Option is B

The Gabriel Phthalimide synthesis is a well-known method for synthesizing primary amines, but it is not effective for preparing aromatic amines. The reason for this is that aryl halides do not undergo nucleophilic substitution reactions with the phthalimide anion. This is due to the poor leaving group ability of the halides in aryl compounds, which hinders the substitution process. However, this issue is not the primary reason why aromatic primary amines cannot be synthesized using this method. \bigskip Step 2: Therefore, while both Assertion (A) and Reason (R) are true, Reason (R) does not correctly explain the statement in Assertion (A). \bigskip