Question

Among the following statements, which is/are TRUE regarding the replication of DNA?

• A. Replication is bidirectional and conservative in nature.
• B. Replication in eukaryotes takes place at multiple Ori sites simultaneously.
• C. Both the strands replicate in discontinuous manner.
• D. Both the strands replicate in semiconservative manner.

Hint:

DNA replication is semiconservative, bidirectional, and semi-discontinuous. Remember: leading strand = continuous; lagging strand = discontinuous.

Answer 1

The Correct Option is B, D

- (A) Incorrect: Replication is semiconservative, not conservative. Each daughter DNA has one parental and one new strand.
- (B) Correct: Eukaryotic DNA replication initiates from multiple origins of replication (Ori sites) simultaneously to speed up replication of large genomes.
- (C) Incorrect: Replication is semi-discontinuous, not fully discontinuous. Leading strand is continuous, lagging strand is discontinuous (Okazaki fragments).
- (D) Correct: DNA replication is universally semiconservative.
\fbox{Therefore, the correct answer is (B) and (D).}