Question

Amides are less basic than amines.

Hint:

The basicity of amines is higher than amides because the lone pair on the nitrogen in amides is less available due to resonance with the carbonyl group.

Answer 1

Amides are less basic than amines because the lone pair of electrons on the nitrogen atom in amides is delocalized into the carbonyl group through resonance. This reduces the availability of the lone pair for protonation, making the nitrogen less basic. In contrast, amines do not have such resonance and their lone pair is more available for protonation, making them more basic than amides.