A rectangle is formed by the lines \[ x = 4, \quad x = -2, \quad y = 5, \quad y = -2 \] and a circle is drawn through the vertices of this rectangle. The pole of the line \[ y + 2 = 0 \] with respect to this circle is:
\( (1, -4) \)
In the given figure, the numbers associated with the rectangle, triangle, and ellipse are 1, 2, and 3, respectively. Which one among the given options is the most appropriate combination of \( P \), \( Q \), and \( R \)?

The center of a circle $ C $ is at the center of the ellipse $ E: \frac{x^2}{a^2} + \frac{y^2}{b^2} = 1 $, where $ a>b $. Let $ C $ pass through the foci $ F_1 $ and $ F_2 $ of $ E $ such that the circle $ C $ and the ellipse $ E $ intersect at four points. Let $ P $ be one of these four points. If the area of the triangle $ PF_1F_2 $ is 30 and the length of the major axis of $ E $ is 17, then the distance between the foci of $ E $ is:
In a messenger RNA molecule, untranslated regions (UTRs) are present at:
I. 5' end before start codon
II. 3' end after stop codon
III. 3' end before stop codon
IV. 5' end after start codon