Question:

A patient presents with sudden onset of chest pain shooting to the neck and interscapularregion. X-ray shows widened mediastinum. BP is 110/90 mmHg in the right upper limb and 160/100 mmHg in the left upper limb. What is the most likely diagnosis?

Updated On: Jun 18, 2025
  • Acute coronary syndrome 

  • Acute pulmonary embolism
  • Acute aortic dissection
  • Esophageal rupture
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The Correct Option is C

Solution and Explanation

A patient arrives with a sudden onset of chest pain radiating to the neck and interscapular region, and an X-ray reveals a widened mediastinum. Additionally, there is a noted blood pressure difference between the limbs: 110/90 mmHg in the right upper limb and 160/100 mmHg in the left upper limb.

Given these symptoms, we analyze each option:

  • Acute coronary syndrome: Typically presents with chest pain but does not explain the widened mediastinum or blood pressure discrepancy between limbs.
  • Acute pulmonary embolism: May cause acute chest pain and respiratory symptoms but usually does not cause mediastinal widening or BP differences.
  • Acute aortic dissection: Characterized by severe chest pain radiating to the back, sudden onset, a widened mediastinum due to aortic involvement, and differing blood pressures in the limbs due to disrupted blood flow.
  • Esophageal rupture: Can present with sudden pain and mediastinal issues but is less likely to cause such significant BP discrepancies.

Conclusion: The symptoms and the X-ray findings of the widened mediastinum, along with the blood pressure discrepancy between the extremities, strongly point to Acute aortic dissection as the most likely diagnosis.

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