Question:

Which of the following drugs is not used for chronic heart failure?

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For chronic heart failure, focus on diuretics, vasodilators, and β-blockers as essential treatments.
Updated On: Sep 26, 2025
  • Diuretics
  • Vasodilators
  • β-Blockers
  • Phosphodiesterase inhibitors
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The Correct Option is D

Solution and Explanation

Step 1: Chronic heart failure treatment.
Chronic heart failure is a condition where the heart is unable to pump blood effectively, leading to fluid buildup and insufficient oxygenation of tissues. The management of this condition involves medications to reduce fluid retention, manage blood pressure, and improve heart function.
Step 2: Diuretics, Vasodilators, and β-Blockers.
- Diuretics are commonly used to reduce fluid buildup in the body, which is a major symptom of heart failure.
- Vasodilators help relax blood vessels, lowering blood pressure and reducing the heart's workload.
- β-Blockers reduce heart rate and improve heart function over time by reducing the heart's oxygen demand. These are essential for chronic heart failure treatment.
Step 3: Phosphodiesterase inhibitors.
Phosphodiesterase inhibitors, like milrinone, are typically used for acute heart failure to increase heart contractility and improve symptoms. They are not used long-term due to their side effects, such as arrhythmias.
Step 4: Conclusion.
Therefore, phosphodiesterase inhibitors are not used for chronic heart failure management.
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