A consensus sequence represents the most common nucleotide or amino acid found at each position in a set of aligned sequences. It is often used in bioinformatics to identify conserved regions in DNA, RNA, or proteins.

In the above represented plasmid an alien piece of DNA is inserted at the EcoRI site. Which of the following strategies will be chosen to select the recombinant colonies?
| List-I (Principle of Extension) | List-II (Description) |
|---|---|
| A. Principle of democratic approach | I. Extension helps people to help themselves. Good extension work is directed towards assisting people to work out their own problems, rather than giving them ready-made solutions |
| B. The grassroots principle of organization | II. People, groups and their conditions differ from place to place. Therefore, extension programmes should be flexible, so that necessary changes can be made whenever needed to meet varying conditions |
| C. Principle of adaptability | III. Participation of people in extension activities is voluntary and development interventions are carried out based on the perceived needs of the people |
| D. Principle of participation | IV. Any development programme should fit in with the local conditions |
