List of top Questions asked in GPAT

All of the following are TNFα inhibitor EXCEPT

Identify the drug that is not among the drug recommended as the 1st time drug in the treatment of Partial seizure with or without generalized seizure

Trastuzumab is a/an

When a New Drug Application (NDA) made?

Which metabolite is used to inactivate the vasico-toxic metabolite leading to hemorrhagic cystitis by alkylating agent used in the treatment of cancer

A neonate suffering from icterus is intravenously administered with phenobarbital. The justification for this therapy is:

Drugs ‘A’, ‘B’ and ‘C’ follow zero order, first order and second order degradation kinetics, respectively, but have the same rate constant. Which of the following statement is true in this respect:

In the process of extraction, if maceration is accomplished by heating the drug and solvent in a close vessel, then this modification is known as _____

Given below are the two statements
Statement I: Glucose‐6‐phosphate can be formed from glucose, but not from glycogen.
Statement II: Glucose‐1‐phosphate may be hydrolyzed to yield free glucose in liver.
Choose the most appropriate answer from the options given below:

Boric acid with molecular weight 61.83 was partitioned between water and amyl alcohol at 25 °C. The amount of boric acid was determined to be 0.24 g in 250 ml of amyl alcohol and 0.32 g in 100 ml water. The partition coefficient of boric acid between water and amyl alcohol, when calculated at molar concentration for each of the solution, is:

Citric acid cycle is the final pathway during the oxidation of _______ .

In the determination of configuration of glucose, Fischer subjected (‐) arabinose to Ruff’s degradation. The four‐carbon sugar obtained by the degradation process was:

Optically active mandelic acid can be synthesized from benzaldehyde in the presence of the enzyme:

Isobutane upon bromination under the influence of ultraviolet light at 127 °C affords the following major product:

Phenol upon treatment with bromine in the presence of carbondisulphide at 0 °C yields:

Identify the functional groups from the below mentioned options that lead to weakening of benzoic acid:
(A):–OH
(B):–Cl
(C):–NH₂
(D):–NO₂

Insertion of a oxygen in a carbonyl compound to form an ester is known as:

Which one of the following is NOT a phospholipid?

The major product formed in the above acid‐catalyzed reaction is:

All enzymes accelerate the reaction rates by______________ .

The major product formed in the above reaction is:

Heme is ____ .

Among the following organic compounds, the one that is non‐aromatic is:

Controlled alkylation of a ketone via an enamine intermediate is named as:

Match List I with List II

	List I-Antigen‐ antibody reaction types		List II-Application
A	Precipitin test	I	Screening for Rubella and Type2 Herpes viruses
B	Agglutination (Haemagglutination)	II	Streptococcal differentiation into serological groups
C	Complement Fixation reaction	III	Serological diagnosis of influenza & mumps viruses
D	ELISA	IV	Treponema pallidum identification
E	-	V	Mycobacterium identification

Choose the correct answer from the options given below: