Question

Insertion of a oxygen in a carbonyl compound to form an ester is known as:

• A. Baeyer Villiger oxidation
• B. Sharpless epoxidation
• C. Prevost oxidation
• D. Lossen rearrangement

Answer 1

The Correct Option is A

The question is asking for the name of the reaction where an oxygen atom is inserted into a carbonyl compound to form an ester. This is a well-known reaction in organic chemistry called the Baeyer Villiger oxidation.

Explanation:

The Baeyer Villiger oxidation is a classical organic reaction that involves the conversion of ketones to esters or cyclic ketones to lactones with the help of a peroxide as an oxygen source. This transformation is facilitated by peroxy acids such as m-chloroperoxybenzoic acid (mCPBA) or hydrogen peroxide in the presence of an acid catalyst. The key feature of this reaction is the migration of an alkyl or aryl group from the carbon atom of the ketone to the adjacent oxygen atom, resulting in the insertion of an oxygen atom into the structure, forming an ester.

Why Baeyer Villiger Oxidation is the Correct Answer:

• Baeyer Villiger oxidation: This is the correct choice because it specifically involves the insertion of oxygen into a carbonyl group to form an ester, matching the process described in the question.
• Sharpless epoxidation: This reaction involves the formation of an epoxide (three-membered cyclic ether) from alkenes using titanium and an oxidizing agent. It does not involve the formation of esters.
• Prevost oxidation: This transforms alkenes into trans-diols and does not involve esters or the insertion of oxygen into a carbonyl group.
• Lossen rearrangement: This is a rearrangement reaction that transforms hydroxamic acids into isocyanates. It also doesn't involve the formation of esters.

Conclusion:

From the above explanations, it is clear that the correct answer is Baeyer Villiger oxidation, as it specifically involves the insertion of an oxygen atom into a carbonyl compound to form an ester.