The linking number (Lk) represents the total twists and writhes of a DNA molecule. Adding +2 to the linking number of relaxed DNA changes the topology and introduces positive supercoiling. The new linking number is Lk = 202, which leads to torsional stress and a more tightly coiled DNA.
| List I | List II |
|---|---|
| (A) Histone erasers | (III) Deacetylases |
| (B) Histone readers | (IV) Bromodomain proteins |
| (C) Histone writers | (I) Methyltransferase |
| (D) DNA unwinding | (II) Topoisomerase |
Match List-I with List-II\[\begin{array}{|c|c|} \hline \textbf{Provision} & \textbf{Case Law} \\ \hline \text{(A) Strict Liability} & \text{(1) Ryland v. Fletcher} \\ \hline \text{(B) Absolute Liability} & \text{(II) M.C. Mehta v. Union of India} \\ \hline \text{(C) Negligence} & \text{(III) Nicholas v. Marsland} \\ \hline \text{(D) Act of God} & \text{(IV) MCD v. Subhagwanti} \\ \hline \end{array}\]
Match Fibre with Application.\[\begin{array}{|l|l|} \hline \textbf{LIST I} & \textbf{LIST II} \\ \textbf{Fibre} & \textbf{Application} \\ \hline \hline \text{A. Silk fibre} & \text{I. Fire retardant} \\ \hline \text{B. Wool fibre} & \text{II. Directional lustre} \\ \hline \text{C. Nomex fibre} & \text{III. Bulletproof} \\ \hline \text{D. Kevlar fibre} & \text{IV. Thermal insulation} \\ \hline \end{array}\]