Question

Match List I with List II:

List I	List II
(A) Histone erasers	(III) Deacetylases
(B) Histone readers	(IV) Bromodomain proteins
(C) Histone writers	(I) Methyltransferase
(D) DNA unwinding	(II) Topoisomerase

Choose the correct answer from the options given below:

• (A) - (II), (B) - (IV), (C) - (I), (D) - (III)
• (A) - (I), (B) - (III), (C) - (II), (D) - (IV)
• (A) - (I), (B) - (II), (C) - (IV), (D) - (III)
• (A) - (III), (B) - (IV), (C) - (I), (D) - (II)

Hint:

Understand the roles of histone modifiers and related proteins in gene expression and chromatin remodeling.

Answer 1

The Correct Option is A

- Histone erasers such as Topoisomerase remove methyl groups from histones, modifying gene expression.
- Histone readers is facilitated by bromodomain proteins that interact with acetylatedlysines.
- Histone writers recognize histone modifications (e.g., acetylation or methylation) to mediate chromatin remodeling.
- DNA unwinding like deacetylases add or remove acetyl groups to regulate DNA accessibility.