Histone H1, often referred to as the linker histone, binds to the DNA that enters and exits the nucleosome core particle, stabilizing the chromatin's higher-order structure. Unlike core histones (H2A, H2B, H3, H4), H1 is not part of the nucleosome octamer but instead associates with the linker DNA between nucleosomes, facilitating chromatin compaction.
List I | List II |
---|---|
(A) Histone erasers | (III) Deacetylases |
(B) Histone readers | (IV) Bromodomain proteins |
(C) Histone writers | (I) Methyltransferase |
(D) DNA unwinding | (II) Topoisomerase |