Question

Which one of the following is the first stable compound in Krebs cycle?

• A. Citric acid
• B. Fumaric acid
• C. Acetyl-CoA
• D. Oxaloacetic acid

Hint:

Citric acid (citrate) is the first stable compound produced in the Krebs cycle, formed by the combination of Acetyl-CoA and oxaloacetate.

Answer 1

The Correct Option is A

Step 1: Understand the Krebs cycle.
The Krebs cycle is a part of cellular respiration that takes place in the mitochondria.
It begins with the combination of Acetyl-CoA and oxaloacetate to form citric acid (also called citrate).
Step 2: Reaction formation.
The reaction begins with the combination of Acetyl-CoA (derived from glucose or fats) with oxaloacetate to form citric acid.
This is the first stable compound formed in the cycle.
Step 3: Review of other options.
Fumaric acid: Fumaric acid is produced later in the Krebs cycle, but not as the first stable compound.
Acetyl-CoA: This is a substrate that enters the cycle but is not the first stable compound.
Oxaloacetic acid: This is the molecule that combines with Acetyl-CoA to form citric acid, but it is not the first stable product.
Thus, the correct answer is (A) Citric acid.