Question

Which one of the following is not true about promoters?

• A. They are sequences of DNA
• B. Bind to RNA polymerase II during transcription
• C. Located between operator and coding region
• D. Mutation of promoter region affects transcription rate

Hint:

Promoters are located upstream of the gene they regulate and play a crucial role in transcription initiation.

Answer 1

The Correct Option is C

Step 1: Understanding Promoters 
A promoter is a specific sequence of DNA that initiates transcription by binding to RNA polymerase and other transcription factors. 
Step 2: Evaluating the Options 
- Option (A): True, as promoters are indeed DNA sequences that facilitate transcription. 
- Option (B): True, RNA polymerase II binds to the promoter during transcription in eukaryotes. 
- Option (C): Incorrect, as the promoter is located upstream of the coding region, not between the operator and coding region (the operator is in prokaryotic operons). 
- Option (D): True, mutations in the promoter region affect the transcription rate. 
Step 3: Conclusion 
Promoters are upstream of the coding region, not between the operator and coding region.