Question:

Which one of the following has the ability to inhibit transcription?

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Rifampicin inhibits RNA polymerase, preventing transcription in prokaryotic cells.
Updated On: Feb 10, 2025
  • Neomycin
  • Kanamycin
  • Rifampicin
  • Quinolones
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Role of Antibiotics 
- Neomycin and Kanamycin inhibit protein synthesis by targeting the ribosome. 
- Rifampicin inhibits transcription by binding to RNA polymerase and preventing RNA synthesis. 
- Quinolones inhibit DNA replication by interfering with DNA gyrase but do not directly affect transcription. 
Step 2: Conclusion 
Rifampicin specifically inhibits transcription.

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