Question:

Which of the following proteins is/are involved in intraflagellar transport?

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Intraflagellar transport involves motor proteins like kinesin for anterograde movement and dynein for retrograde movement, all along microtubules.
Updated On: Apr 11, 2025
  • Microtubules
  • Myosin
  • Actin
  • Kinesin
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The Correct Option is A, D

Solution and Explanation

Intraflagellar transport (IFT) is a mechanism that moves cargo along microtubules to assemble and maintain cilia and flagella. The key proteins involved in IFT are:

Step 1: Microtubules
Microtubules are the structural components that form the "tracks" for intraflagellar transport. They provide the structural framework along which cargo is transported.
Thus, \( \boxed{A} \) is correct.

Step 2: Kinesin
Kinesin is a motor protein that moves cargo toward the plus end of microtubules (anterograde transport) during IFT.
Thus, \( \boxed{D} \) is correct.

Step 3: Myosin
Myosin is involved in actin filament-based transport, not in intraflagellar transport along microtubules.
Thus, \( \boxed{B} \) is incorrect.

Step 4: Actin
Actin is not involved in intraflagellar transport, as IFT relies on microtubules.
Thus, \( \boxed{C} \) is incorrect.

Final Answer:
The correct answers are \( \boxed{A}, \boxed{D} \).
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