Question:

Which of the following is the opsonin?

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C3b is the opsonin that enhances phagocytosis by marking pathogens for immune cell recognition.
Updated On: Feb 10, 2025
  • C5b
  • C1q
  • C3a
  • C3b
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The Correct Option is D

Solution and Explanation

Step 1: Understanding Opsonins 
Opsonins are molecules that enhance phagocytosis by marking pathogens for recognition by immune cells like macrophages and neutrophils. 
Step 2: Evaluating the Options 
- C5b: Part of the complement system, involved in the formation of the membrane attack complex, not an opsonin. 
- C1q: Part of the complement system, helps initiate the classical pathway but not directly involved in opsonization. 
- C3a: Involved in inflammation but not an opsonin. 
- C3b: Correct, C3b is an opsonin that binds to pathogens, promoting their uptake by phagocytes. 
Step 3: Conclusion 
C3b acts as the primary opsonin in the immune response.

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