Question

Which of the following is the gold standard investigation for diagnosing multiple sclerosis?

• A. CT scan of the brain
• B. MRI with gadolinium
• C. Lumbar puncture
• D. EEG

Hint:

For demyelinating diseases like MS, prioritize MRI for dissemination in space and time criteria.

Answer 1

The Correct Option is B

Step 1: Understanding the question.
The question seeks the gold standard for diagnosing multiple sclerosis, which involves detecting demyelinating lesions. MRI with gadolinium highlights active lesions.
Step 2: Analyzing the options.
(A) CT scan of the brain: CT is less sensitive for MS lesions.
(B) MRI with gadolinium: Correct — It is the gold standard for visualizing plaques in the brain and spinal cord.
(C) Lumbar puncture: Useful for oligoclonal bands but not the gold standard.
(D) EEG: Not relevant for MS diagnosis.
Step 3: Conclusion.
The correct answer is (B) MRI with gadolinium, as it is the gold standard for diagnosing multiple sclerosis.