Question:

Which of the following is not related to drug- enzyme interaction?

Updated On: Apr 9, 2025
  • Enzyme inhibitor
  • Allosteric site
  • Antagonist
  • Co-enzymes
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The Correct Option is D

Approach Solution - 1

Enzyme inhibitors, allosteric sites, and antagonists all play roles in drug-enzyme interactions. Enzyme inhibitors block the active site or allosteric site, preventing the enzyme from functioning. Antagonists interfere with the enzyme's normal activity. Co-enzymes, however, are organic molecules that assist enzymes in catalyzing reactions but are not directly involved in drug-enzyme interactions.

The correct option is (D): Co-enzymes

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Approach Solution -2

Enzyme inhibitor: These are molecules that bind to enzymes and decrease their activity, either by blocking the active site or changing the enzyme's structure. Drug-enzyme interactions often involve inhibitors, making this option relevant.
 
Allosteric site: This is a specific site on an enzyme where a molecule can bind, causing a change in the enzyme's activity. Many drugs target the allosteric site to regulate enzyme function, so this is also related to drug-enzyme interactions.

Antagonist: An antagonist is a substance that blocks or reduces the effect of a biological response. In the context of drug-enzyme interactions, antagonists can inhibit enzyme activity or block receptor binding sites.

Co-enzymes: Co-enzymes are small organic molecules that assist enzymes in their catalytic activity. However, they are not directly involved in drug-enzyme interactions. Co-enzymes are typically involved in metabolic processes but are not classified as drugs in enzyme inhibition or activation.

Thus, co-enzymes are not directly related to drug-enzyme interactions.

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