Crystallization is not a method for solubility enhancement. In fact, crystallization is typically used to purify compounds and reduce solubility in a solvent. In contrast, co-solvency, salt formation, and hydrotropy are methods used to improve the solubility of poorly soluble drugs.
Solvent | Boiling Point (K) |
---|---|
Chloroform | 334.4 |
Diethyl Ether | 307.8 |
Benzene | 353.3 |
Carbon disulphide | 319.4 |
Match the following Class and their Drug:
(1) Alkylating (P) 5-fluorouracil
(2) Platinum analog (Q) Cisplatin
(3) Antimetabolite (R) Cetuximab
(4) EGF receptor inhibitor (S) Chlorambucil