Step 1: Understanding the characteristics of an ideal drug.
An ideal drug should target the affected site, cause minimal side effects, and be harmless to the host while effectively destroying harmful organisms.
Step 2: Analyzing the options.
(A) Should destroy harmful organisms: This is a characteristic of an ideal drug.
(B) Should not disturb physiological process: Correct — An ideal drug should not disrupt the normal physiological processes.
(C) Harmless to host: Correct — An ideal drug must not harm the host.
(D) Is not localized to the affected site: Incorrect — An ideal drug should be localized to the affected site for maximum efficacy.
Step 3: Conclusion.
The correct answer is (D) Is not localized to the affected site.