Question

Which of the following is an unusual feature of the replication cycle in coronaviruses?

• A. \( \text{The RNAs all terminate in a common 3' and produce nested set transcripts} \)
• B. \( \text{They take advantage of recombination with the long RNA genome} \)
• C. \( \text{They are not highly mutable} \)
• D. \( \text{They use capped cellular mRNAs} \)

Hint:

Nested set transcription in coronaviruses enhances viral protein expression, aiding in replication and survival.

Answer 1

The Correct Option is A

Coronaviruses exhibit a unique replication strategy that involves producing a nested set of subgenomic RNAs. These RNAs share a common 3'-end, allowing for efficient gene expression during viral replication. This feature contributes to the complexity of coronavirus transcription mechanisms.