Question

Which of the following drug does not cross the placenta?

• A. Warfarin
• B. Heparin
• C. Phenindione
• D. Bromocriptine

Hint:

Heparin is a low molecular weight drug that does not cross the placenta, making it safe for pregnant women.

Answer 1

The Correct Option is B

Step 1: Understanding drug placental crossing.
Heparin, unlike Warfarin, does not cross the placenta. This is why it is preferred for use in pregnant women for conditions like deep vein thrombosis, as it does not pose a risk to the fetus.
Step 2: Analyzing the options.
(1) Warfarin: Incorrect, Warfarin does cross the placenta and can cause harm to the developing fetus.
(2) Heparin: Correct — Heparin does not cross the placenta, making it safe for use during pregnancy.
(3) Phenindione: Incorrect, Phenindione crosses the placenta and has similar risks to Warfarin.
(4) Bromocriptine: Incorrect, Bromocriptine can cross the placenta.
Step 3: Conclusion.
The correct answer is (2) Heparin.