Question

Which of the following drug is effective in intestinal amoebiasis?

• A. \( \text{Chloroquine} \)
• B. \( \text{Dihydroemetine} \)
• C. \( \text{Diloxanide} \)
• D. \( \text{Tinidazole} \)

Hint:

Think of Diloxanide for clearing the cysts in the intestine, especially in asymptomatic cases.

Answer 1

The Correct Option is C

Diloxanide furoate is an antiamoebic drug specifically effective against the cyst form of *Entamoeba histolytica* in the intestinal lumen. It is often used to treat asymptomatic carriers of amoebiasis and is effective in eradicating the infection from the intestine. Chloroquine is primarily used for malaria and extraintestinal amoebiasis (like amoebic liver abscess). Dihydroemetine is effective against both intestinal and extraintestinal amoebiasis but has significant toxicity. Tinidazole is a nitroimidazole antibiotic and antiprotozoal agent effective against various protozoa, including *E. histolytica*, but diloxanide is particularly useful for luminal amoebiasis.