Question

Which of the following can result in dactylitis

• A. Hemophilia
• B. Von willebrand disease 1
• C. Measles
• D. Sickle Cell Anemia

Answer 1

The Correct Option is D

Sickle Cell Anemia is the condition that can result in dactylitis. Dactylitis, also known as "sausage digits," is a medical condition characterized by the inflammation of an entire digit (finger or toe). It is commonly associated with diseases that cause bone and joint inflammation or blood flow issues.

Pathophysiology: In Sickle Cell Anemia, an inherited red blood cell disorder, abnormal hemoglobin (hemoglobin S) causes red blood cells to become rigid, sticky, and sickle-shaped. These sickle-shaped cells can block blood flow in small blood vessels, leading to pain and inflammation, which may manifest as dactylitis, particularly in children.

Conclusion: While conditions like Hemophilia and Von Willebrand Disease are related to bleeding disorders, and Measles is a viral infection, Sickle Cell Anemia directly correlates with the development of dactylitis due to its characteristic blockage of blood vessels and associated pain episodes.