Question:
Which of the following antidiabetic agent primarily enhances insulin sensitivity in target tissues?
Which of the following antidiabetic agent primarily enhances insulin sensitivity in target tissues?
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Thiazolidinediones = insulin sensitizers. They act via PPAR-$\gamma$ activation to reduce insulin resistance.
Updated On: Jun 16, 2025
- Sulfonylureas
- Biguanides
- Thiazolidinediones
- Alpha-glucosidase inhibitors
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The Correct Option is C
Solution and Explanation
Thiazolidinediones (like pioglitazone) are antidiabetic drugs that work by enhancing insulin sensitivity in muscle, adipose tissue, and the liver. They activate PPAR-$\gamma$ receptors, improving glucose uptake and utilization.
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