Question:
Which enzyme is targeted by beta-lactam antibiotics?
Which enzyme is targeted by beta-lactam antibiotics?
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Transpeptidase is also known as penicillin-binding protein (PBP) — the main target of beta-lactam antibiotics.
Updated On: Jun 16, 2025
- DNA gyrase
- Transpeptidase
- Reverse transcriptase
- Topoisomerase
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The Correct Option is B
Solution and Explanation
Beta-lactam antibiotics, such as penicillins and cephalosporins, inhibit the enzyme transpeptidase, which is crucial for bacterial cell wall synthesis. Blocking this enzyme weakens the cell wall, leading to bacterial lysis.
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