Question

Which enzyme is primarily responsible for relieving supercoiling during DNA replication?

• A. DNA helicase
• B. DNA ligase
• C. DNA polymerase
• D. Topoisomerase

Hint:

Topoisomerases help prevent DNA from becoming tangled during replication by managing supercoiling.

Answer 1

The Correct Option is D

Step 1: Understand the role of topoisomerase.
Topoisomerase is the enzyme that relieves the tension and supercoiling in DNA by making transient cuts to the DNA strands and then rejoining them. This process is crucial during DNA replication.