Question:

Which algorithm is most commonly used for pairwise sequence alignment?

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Needleman-Wunsch is used for global alignment, whereas Smith-Waterman is used for local alignment.
Updated On: Jun 18, 2025
  • BLAST
  • Smith-Waterman
  • Needleman-Wunsch
  • Hidden Markov Model
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The Correct Option is C

Solution and Explanation

The Needleman-Wunsch algorithm is widely used for pairwise sequence alignment, specifically for aligning biological sequences such as DNA, RNA, or protein sequences. It uses dynamic programming to find the optimal global alignment between two sequences.
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