Question

What is the most prominent side effect of salbutamol?

• A. \( \text{Rise in blood pressure} \)
• B. \( \text{Muscle cramps} \)
• C. \( \text{Hyperglycaemia} \)
• D. \( \text{Stimulation of central nervous system} \)

Hint:

Think of the "shake" or "tremor" feeling sometimes associated with inhalers – that relates to muscle effects.

Answer 1

The Correct Option is B

Salbutamol is a short-acting $\beta_2$-adrenergic receptor agonist used primarily as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). While salbutamol can have systemic effects due to $\beta_2$ receptor stimulation outside the lungs, the most prominent side effect is often muscle cramps or tremors. Other potential side effects include tachycardia (increased heart rate), palpitations, nervousness, and hypokalemia (low potassium levels), which can indirectly contribute to muscle issues. A rise in blood pressure is less common, and while it can affect glucose metabolism, hyperglycaemia is not the most prominent side effect. Central nervous system stimulation can occur but is usually less pronounced than muscle-related effects.